\u8fd1\u5e74\u6765\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u79d1\u5b66\u5bb6\u4eec\u5f00\u59cb\u4f7f\u7528\u4eba\u5de5\u667a\u80fd\u6280\u672f\u52a0\u901f\u591a\u9879\u9886\u57df\u7684\u7814\u7a76\uff0c\u5f53\u7136\u4e86\u4ed6\u4eec\u4e5f\u53d6\u5f97\u4e86\u5f88\u591a\u7814\u7a76\u6210\u679c\uff0c\u672c\u6587\u4e2d\uff0c\u5c0f\u7f16\u5c31\u5bf9\u8fd1\u671f\u76f8\u5173\u7814\u7a76\u6210\u679c\u8fdb\u884c\u6574\u7406\uff0c\u4e0e\u5927\u5bb6\u4e00\u8d77\u5b66\u4e60\uff01<\/p>\n
\u30101\u3011Com Biol Med\uff1a\u4eba\u5de5\u667a\u80fd\u5e2e\u52a9\u6cbb\u7597<\/strong>\u7cd6\u5c3f\u75c5<\/strong>\u5f15\u53d1\u7684\u773c\u75be<\/strong><\/p>\n doi\uff1a10.1016\/j.compbiomed.2018.10.031<\/p>\n \u6839\u636e\u6700\u8fd1\u7684\u4e00\u9879\u7814\u7a76\uff0c\u7814\u7a76\u4eba\u5458\u5df2\u7ecf\u4f7f\u7528\u4eba\u5de5\u667a\u80fd\u8bca\u65ad\u65e9\u671f\u9636\u6bb5\u7684\u7cd6\u5c3f\u75c5\u5f15\u53d1\u7684\u5931\u660e\u75c7\u72b6\u3002<\/p>\n \u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8\u662f\u6210\u4eba\u89c6\u529b\u4e27\u5931\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u5176\u5f71\u54cd\u6b63\u5728\u5168\u7403\u8303\u56f4\u5185\u6269\u5927\uff0c\u52302030\u5e74\u5c06\u67091.91\u4ebf\u4eba\u53d7\u5230\u5f71\u54cd\u3002\u5728\u75be\u75c5\u65e9\u671f\uff0c\u867d\u7136\u6ca1\u6709\u660e\u663e\u75c7\u72b6\uff0c\u4f46\u75be\u75c5\u53ef\u80fd\u5df2\u7ecf\u53d1\u5c55\u3002\u65e9\u671f\u8bca\u65ad\u548c\u6cbb\u7597\u53ef\u4ee5\u5bf9\u60a3\u8005\u4fdd\u6301\u591a\u5c11\u89c6\u529b\u4ea7\u751f\u663e\u7740\u5f71\u54cd\u3002<\/p>\n \u7814\u7a76\u4eba\u5458\u5f00\u53d1\u4e86\u4e00\u79cd\u56fe\u50cf\u5904\u7406\u7b97\u6cd5\uff0c\u53ef\u4ee5\u81ea\u52a8\u68c0\u6d4b\u75be\u75c5\u7684\u4e00\u4e2a\u5173\u952e\u75c7\u72b6\uff0c\u5373\u89c6\u7f51\u819c\u4e0a\u7684\u6db2\u4f53\uff0c\u51c6\u786e\u7387\u4e3a98\uff05\u3002\u8be5\u7814\u7a76\u7684\u9996\u5e2d\u7814\u7a76\u5458\uff0c\u58a8\u5c14\u672c\u7687\u5bb6\u7406\u5de5\u5927\u5b66Dinesh Kant Kumar\u6559\u6388\u8868\u793a\uff0c\u8fd9\u79cd\u65b9\u6cd5\u662f\u5373\u65f6\u4e14\u5177\u6709\u6210\u672c\u6548\u76ca\u7684\u3002<\/p>\n \u30102\u3011PLoS ONE\uff1a\u79d1\u5b66\u5bb6\u6709\u671b\u5229\u7528\u4eba\u5de5\u667a\u80fd\u6280\u672f\u66f4\u597d\u5730\u7ba1\u7406\u764c\u75c7\u60a3\u8005<\/strong><\/p>\n doi\uff1a10.1371\/journal.pone.0208808<\/p>\n \u8fd1\u65e5\uff0c\u4e00\u9879\u520a\u767b\u5728\u56fd\u9645\u6742\u5fd7PLOS ONE\u4e0a\u7684\u7814\u7a76\u62a5\u544a\u4e2d\uff0c\u6765\u81ea\u8428\u91cc\u5927\u5b66\u7b49\u673a\u6784\u7684\u79d1\u5b66\u5bb6\u4eec\u901a\u8fc7\u7814\u7a76\u5f00\u53d1\u51fa\u4e86\u4e00\u79cd\u65b0\u578b\u7684\u4eba\u5de5\u667a\u80fd\u7cfb\u7edf\uff08AI\uff09\uff0c\u5176\u6709\u671b\u9884\u6d4b\u764c\u75c7\u60a3\u8005\u5728\u6574\u4e2a\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u7684\u75be\u75c5\u75c7\u72b6\u548c\u4e25\u91cd\u7a0b\u5ea6\u3002<\/p>\n \u6587\u7ae0\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u8be6\u7ec6\u63cf\u8ff0\u4e86\u4ed6\u4eec\u5f00\u53d1\u7684\u4e24\u79cd\u673a\u5668\u5b66\u4e60\u6a21\u578b\u5982\u4f55\u51c6\u786e\u9884\u6d4b\u764c\u75c7\u60a3\u8005\u6240\u9762\u4e34\u7684\u4e09\u79cd\u75be\u75c5\u75c7\u72b6\u7684\u4e25\u91cd\u6027\uff0c\u8fd9\u4e09\u79cd\u75c7\u72b6\u5305\u62ec\u6291\u90c1\u3001\u7126\u8651\u548c\u7761\u7720\u969c\u788d\uff0c\u8fd9\u4e9b\u75c7\u72b6\u5747\u4e0e\u764c\u75c7\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u7684\u660e\u663e\u4e0b\u964d\u76f4\u63a5\u76f8\u5173\u3002\u7814\u7a76\u8005\u5206\u6790\u4e86\u764c\u75c7\u60a3\u8005\u5728\u63a5\u53d7\u8ba1\u7b97\u673a\u65ad\u5c42\u626b\u63cfx\u5c04\u7ebf\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u6240\u7ecf\u5386\u7684\u75c7\u72b6\u548c\u76f8\u5173\u6570\u636e\uff0c\u968f\u540e\u5728\u4e0d\u540c\u7684\u65f6\u95f4\u6bb5\u6765\u68c0\u6d4b\u662f\u5426\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\u80fd\u51c6\u786e\u9884\u6d4b\u60a3\u8005\u7684\u75be\u75c5\u75c7\u72b6\u8868\u73b0\u3002<\/p>\n \u30103\u3011Cancer Res\uff1a\u5f00\u53d1\u51fa\u53ef\u9ad8\u6548\u8bc6\u522b\u4e0d\u540c\u7c7b\u578b\u764c\u7ec6\u80de\u7684\u4eba\u5de5\u667a\u80fd\u7cfb\u7edf<\/strong><\/p>\n doi\uff1a10.1158\/0008-5472.CAN-18-0653<\/p>\n \u5728\u764c\u75c7\u60a3\u8005\u4e2d\uff0c\u764c\u7ec6\u80de\u7684\u7c7b\u578b\u5728\u4e0d\u540c\u60a3\u8005\u4e4b\u95f4\u5b58\u5728\u5f88\u5927\u5dee\u5f02\uff0c\u751a\u81f3\u5728\u540c\u4e00\u79cd\u75be\u75c5\u4e2d\u4e5f\u662f\u5982\u6b64\uff1b\u8bc6\u522b\u764c\u75c7\u60a3\u8005\u673a\u4f53\u4e2d\u5b58\u5728\u7684\u7279\u6b8a\u7ec6\u80de\u7c7b\u578b\u5bf9\u4e8e\u9009\u62e9\u6700\u4f73\u7684\u7597\u6cd5\u6765\u6709\u6548\u6cbb\u7597\u60a3\u8005\u81f3\u5173\u91cd\u8981\uff0c\u4f46\u80fd\u591f\u5b8c\u6210\u8fd9\u9879\u4efb\u52a1\u7684\u65b9\u6cd5\u5374\u662f\u975e\u5e38\u8d39\u65f6\u7684\uff0c\u800c\u4e14\u5e38\u5e38\u4f1a\u56e0\u4eba\u4e3a\u9519\u8bef\u548c\u4eba\u7c7b\u89c6\u91ce\u7684\u5c40\u9650\u6027\u800c\u88ab\u963b\u788d\u3002<\/p>\n \u8fd1\u65e5\uff0c\u4e00\u9879\u520a\u767b\u5728\u56fd\u9645\u6742\u5fd7Cancer Research\u4e0a\u7684\u7814\u7a76\u62a5\u544a\u4e2d\uff0c\u6765\u81ea\u65e5\u672c\u5927\u962a\u5927\u5b66\u7684\u79d1\u5b66\u5bb6\u4eec\u901a\u8fc7\u7814\u7a76\u63ed\u793a\u4e86\u5982\u4f55\u901a\u8fc7\u4e00\u79cd\u57fa\u4e8e\u4eba\u5de5\u667a\u80fd\u7684\u7cfb\u7edf\u6765\u514b\u670d\u4e0a\u8ff0\u95ee\u9898\uff0c\u7814\u7a76\u8005\u6307\u51fa\uff0c\u8fd9\u79cd\u57fa\u4e8e\u4eba\u5de5\u667a\u80fd\u7684\u7cfb\u7edf\u80fd\u901a\u8fc7\u626b\u63cf\u663e\u5fae\u56fe\u50cf\u5e76\u83b7\u5f97\u6bd4\u4eba\u7c7b\u5224\u65ad\u66f4\u9ad8\u7684\u51c6\u786e\u7387\uff0c\u6765\u6709\u6548\u8bc6\u522b\u4e0d\u540c\u7c7b\u578b\u7684\u764c\u7ec6\u80de\uff0c\u8fd9\u79cd\u65b9\u6cd5\u6216\u80fd\u7ed9\u80bf\u7624\u5b66\u9886\u57df\u7684\u7814\u7a76\u5e26\u6765\u9769\u547d\u6027\u7684\u7a81\u7834\u3002<\/p>\n \u30104\u3011Bioinformatics\uff1a\u65b0\u578b\u4eba\u5de5\u667a\u80fd\u7cfb\u7edf\u6709\u671b\u52a0\u901f\u79d1\u5b66\u5bb6\u4eec\u5728\u764c\u75c7\u9886\u57df\u7684\u7814\u7a76<\/strong><\/p>\n doi\uff1a10.1093\/bioinformatics\/bty845<\/p>\n \u8fd1\u65e5\uff0c\u4e00\u9879\u520a\u767b\u5728\u56fd\u9645\u6742\u5fd7Bioinformatics\u4e0a\u7684\u7814\u7a76\u62a5\u544a\u4e2d\uff0c\u6765\u81ea\u5251\u6865\u5927\u5b66\u7684\u79d1\u5b66\u5bb6\u4eec\u901a\u8fc7\u7814\u7a76\u5f00\u53d1\u4e86\u4e00\u79cd\u540d\u4e3a\u201cLION LBD\u201d\u7684\u65b0\u578bAI\u7cfb\u7edf(\u4eba\u5de5\u667a\u80fd\u7cfb\u7edf)\uff0c\u5176\u80fd\u5e2e\u52a9\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u8fdb\u884c\u764c\u75c7\u76f8\u5173\u7684\u7814\u7a76\u3002<\/p>\n \u76ee\u524d\u764c\u75c7\u7814\u7a76\u5728\u5168\u7403\u8303\u56f4\u5185\u5438\u5f15\u4e86\u5927\u91cf\u7684\u8d44\u91d1\uff0c\u800c\u4e14\u76f8\u5173\u7814\u7a76\u62a5\u544a\u7684\u6570\u91cf\u4e5f\u975e\u5e38\u5e9e\u5927\uff0c\u56e0\u6b64\u7814\u7a76\u4eba\u5458\u6b63\u5728\u594b\u529b\u8fdb\u884c\u764c\u75c7\u9886\u57df\u76f8\u5173\u7684\u7814\u7a76\uff0c\u800c\u4ed6\u4eec\u5e38\u5e38\u4f1a\u53d1\u73b0\uff0c\u5f88\u591a\u6279\u5224\u6027\u5047\u8bbe\u7684\u8bc1\u636e\u5f80\u5f80\u662f\u5728\u6587\u7ae0\u53d1\u8868\u4e4b\u540e\u624d\u4f1a\u88ab\u53d1\u73b0\u3002<\/p>\n \u764c\u75c7\u662f\u4e00\u79cd\u975e\u5e38\u590d\u6742\u7684\u75be\u75c5\uff0c\u5176\u5728\u5168\u7403\u662f\u8bf1\u53d1\u4eba\u7fa4\u6b7b\u4ea1\u7684\u7b2c\u4e8c\u5927\u539f\u56e0\uff0c\u76ee\u524d\u7814\u7a76\u4eba\u5458\u5e76\u6ca1\u6709\u5b8c\u5168\u5bf9\u764c\u75c7\u8fdb\u884c\u6df1\u5165\u5256\u6790\uff1b\u764c\u75c7\u7684\u53d1\u751f\u5305\u62ec\u591a\u79cd\u5316\u5b66\u548c\u751f\u7269\u5316\u5b66\u5206\u5b50\u3001\u53cd\u5e94\u4ee5\u53ca\u591a\u79cd\u901a\u8def\u7684\u6539\u53d8\uff0c\u7814\u7a76\u4eba\u5458\u5728\u591a\u4e2a\u5e7f\u6cdb\u7684\u5b66\u79d1\u4e2d\u8fdb\u884c\u764c\u75c7\u7814\u7a76\uff0c\u800c\u5176\u5728\u63cf\u8ff0\u76f8\u4f3c\u6982\u5ff5\u7684\u65b9\u5f0f\u4e0a\u4e5f\u5404\u4e0d\u76f8\u540c\u3002<\/p>\n \u30105\u3011Science\uff1a\u5229\u7528\u4eba\u5de5\u667a\u80fd\u9884\u6d4bRNA\u75c5\u6bd2\u7684\u52a8\u7269\u5bbf\u4e3b\u548c\u4f20\u64ad\u5a92\u4ecb<\/strong><\/p>\n doi\uff1a10.1126\/science.aap9072<\/p>\n \u8bf8\u5982\u57c3\u535a\u62c9\u75c5\u6bd2\u548c\u5be8\u5361\u75c5\u6bd2\u4e4b\u7c7b\u7684\u8bb8\u591a\u81f4\u547d\u6027\u7684\u548c\u65b0\u51fa\u73b0\u7684\u75c5\u6bd2\u4f20\u64ad\u7ed9\u4eba\u7c7b\u5e76\u5bfc\u81f4\u4e25\u91cd\u75be\u75c5\u4e4b\u524d\u65e9\u5c31\u5728\u91ce\u751f\u52a8\u7269\u548c\u6606\u866b\u7fa4\u843d\u4e2d\u4f20\u64ad\u3002\u4ece\u57fa\u56e0\u7ec4\u5e8f\u5217\u4e2d\u5bfb\u627e\u4e0d\u540c\u75c5\u6bd2\u7684\u52a8\u7269\u548c\u6606\u866b\u5bbf\u4e3b\u53ef\u80fd\u9700\u8981\u591a\u5e74\u7684\u5bc6\u96c6\u7684\u5b9e\u5730\u7814\u7a76\u548c\u5b9e\u9a8c\u5ba4\u5de5\u4f5c\u3002\u7531\u6b64\u5f15\u8d77\u7684\u5ef6\u8fdf\u610f\u5473\u7740\u96be\u4ee5\u5b9e\u65bd\u9884\u9632\u63aa\u65bd\uff0c\u6bd4\u5982\u7ed9\u75be\u75c5\u7684\u52a8\u7269\u6765\u6e90\u63a5\u79cd\u75ab\u82d7\uff0c\u6216\u8005\u963b\u6b62\u7269\u79cd\u4e4b\u95f4\u7684\u5371\u9669\u63a5\u89e6\u3002\u56e0\u6b64\uff0c\u5728\u5f53\u524d\uff0c\u53ca\u65f6\u5730\u627e\u5230\u8fd9\u4e9b\u5929\u7136\u75c5\u6bd2\u5bbf\u4e3b—\u8fd9\u53ef\u80fd\u6709\u52a9\u4e8e\u963b\u6b62\u5411\u4eba\u7c7b\u4f20\u64ad—\u5bf9\u79d1\u5b66\u5bb6\u4eec\u6784\u6210\u4e86\u5de8\u5927\u7684\u6311\u6218\u3002<\/p>\n \u5982\u4eca\uff0c\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u82cf\u683c\u5170\u683c\u62c9\u65af\u54e5\u5927\u5b66\u7b49\u7814\u7a76\u673a\u6784\u7684\u7814\u7a76\u4eba\u5458\u8bbe\u8ba1\u51fa\u4e00\u79cd\u65b0\u7684\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\uff0c\u5b83\u5229\u7528\u75c5\u6bd2\u57fa\u56e0\u7ec4\u5e8f\u5217\u9884\u6d4b\u4e00\u7cfb\u5217RNA\u75c5\u6bd2\u7684\u53ef\u80fd\u7684\u81ea\u7136\u5bbf\u4e3b\uff0c\u5176\u4e2dRNA\u75c5\u6bd2\u662f\u6700\u5e38\u89c1\u7684\u4ece\u75c5\u6bd2\u8df3\u8dc3\u5230\u4eba\u7c7b\u4e2d\u7684\u75c5\u6bd2\u7fa4\u4f53\u3002\u76f8\u5173\u7814\u7a76\u7ed3\u679c\u53d1\u8868\u57282018\u5e7411\u67082\u65e5\u7684Science\u671f\u520a\u4e0a\u3002<\/p>\n \u30106\u3011Adv Therap\uff1a\u4eba\u5de5\u667a\u80fd\u52a9\u529b\u8f6c\u79fb\u6027<\/strong>\u524d\u5217\u817a\u764c<\/strong>\u6cbb\u7597\uff0c\u7597\u6548\u663e\u8457<\/strong><\/p>\n doi\uff1a10.1002\/adtp.201800104<\/p>\n \u8054\u5408\u5316\u7597\u662f\u764c\u75c7\u6cbb\u7597\u4e4b\u8def\u4e0a\u7684\u4e00\u5757\u91cc\u7a0b\u7891\uff0c\u4f46\u662f\u4f18\u5316\u5176\u7597\u6548\u9700\u8981\u5bf9\u836f\u7269\u7684\u534f\u540c\u4f5c\u7528\u8fdb\u884c\u5242\u91cf\u548c\u65f6\u95f4\u76f8\u5173\u7684\u8c03\u6574\uff0c\u4f20\u7edf\u7684\u57fa\u4e8e\u5b9e\u9a8c\u7684\u8c03\u6574\u65b9\u6cd5\u8017\u65f6\u53c8\u8017\u529b\uff0c\u6548\u7387\u6781\u4f4e\uff0c\u963b\u788d\u4e86\u6700\u4f73\u8054\u5408\u7597\u6cd5\u7684\u53d1\u5c55\u3002<\/p>\n \u4e3a\u6b64\uff0c\u7814\u7a76\u4eba\u5458\u8fd1\u65e5\u5f00\u53d1\u51fa\u4e86\u4e00\u79cd\u57fa\u4e8e\u4eba\u5de5\u667a\u80fd\uff08AI\uff09\u7684\u5e73\u53f0\u2014\u2014CURATE AI\u6765\u5b8c\u5584\u5e76\u52a0\u901f\u8fd9\u4e2a\u8fc7\u7a0b\u3002\u5728\u4ed6\u4eec\u7684\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u4e86\u6eb4\u7ed3\u6784\u57df\u6291\u5236\u5242ZEN-3694\u548c\u96c4\u6fc0\u7d20\u53d7\u4f53\u62ee\u6297\u5242\u6069\u6742\u9c81\u80fa\uff08enzalutamide\uff09\u8fd9\u4e24\u4e2a\u836f\u7269\u4f5c\u4e3a\u6a21\u5f0f\u836f\u7269\uff0c\u5229\u7528\u8fd9\u79cd\u65b0\u7684AI\u5e73\u53f0\u5bf9\u8054\u5408\u5b83\u4eec\u6cbb\u7597\u4e00\u540d\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c\u75c5\u4eba\u7684\u7528\u836f\u65b9\u9488\u8fdb\u884c\u4e86\u6307\u5bfc\uff0c\u76ee\u7684\u5728\u4e8e\u964d\u4f4e\u75c5\u4eba\u8840\u6e05\u4e2d\u7684\u524d\u5217\u817a\u7279\u5f02\u6027\u6297\u539f\uff08PSA\uff09\u3002<\/p>\n \u30107\u3011Lancet Oncol\uff1a\u4eba\u5de5\u667a\u80fd\u5e2e\u52a9\u9884\u6d4b\u764c\u75c7\u60a3\u8005\u63a5\u53d7\u514d\u75ab\u6cbb\u7597\u7684\u6548\u679c<\/strong><\/p>\n doi\uff1a10.1016\/S1470-2045(18)30413-3<\/p>\n \u53d1\u8868\u5728\u300aLancet Oncology\u300b\u4e0a\u7684\u4e00\u9879\u7814\u7a76\u9996\u6b21\u8bc1\u5b9e\uff0c\u4eba\u5de5\u667a\u80fd\u53ef\u4ee5\u5904\u7406\u533b\u5b66\u56fe\u50cf\u4ee5\u63d0\u53d6\u751f\u7269\u5b66\u548c\u4e34\u5e8a\u4fe1\u606f\u3002\u901a\u8fc7\u8bbe\u8ba1\u7b97\u6cd5\u5e76\u5c06\u5176\u5f00\u53d1\u7528\u4e8e\u5206\u6790CT\u626b\u63cf\u56fe\u50cf\u4f5c\u8005\u7b49\u4eba\u521b\u5efa\u4e86\u4e00\u4e2a\u6240\u8c13\u7684\u653e\u5c04\u5b66\u7279\u5f81\u3002\u8be5\u7279\u5f81\u5b9a\u4e49\u4e86\u80bf\u7624\u7684\u6dcb\u5df4\u7ec6\u80de\u6d78\u6da6\u6c34\u5e73\uff0c\u5e76\u63d0\u4f9b\u4e86\u60a3\u8005\u514d\u75ab\u6cbb\u7597\u529f\u6548\u7684\u9884\u6d4b\u8bc4\u5206\u3002<\/p>\n \u5c06\u6765\uff0c\u533b\u751f\u53ef\u80fd\u56e0\u6b64\u80fd\u591f\u4f7f\u7528\u6210\u50cf\u6765\u8bc6\u522b\u4f4d\u4e8e\u8eab\u4f53\u4efb\u4f55\u90e8\u4f4d\u7684\u80bf\u7624\u4e2d\u7684\u751f\u7269\u73b0\u8c61\uff0c\u800c\u65e0\u9700\u8fdb\u884c\u6d3b\u7ec4\u7ec7\u68c0\u67e5\u3002\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u6ca1\u6709\u6807\u8bb0\u53ef\u4ee5\u51c6\u786e\u5730\u8bc6\u522b\u90a3\u4e9b\u5bf9PD-1 \/ PD-L1\u514d\u75ab\u6cbb\u7597\u6709\u53cd\u5e94\u7684\u60a3\u8005\uff0c\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u53ea\u670915\uff05\u81f330\uff05\u7684\u60a3\u8005\u5bf9\u6b64\u7c7b\u6cbb\u7597\u6709\u53cd\u5e94\u3002\u4f17\u6240\u5468\u77e5\uff0c\u80bf\u7624\u73af\u5883\u4e2d\u514d\u75ab\u7ec6\u80de\u66f4\u4e30\u5bcc\uff08\u6dcb\u5df4\u7ec6\u80de\u7684\u5b58\u5728\uff09\uff0c\u514d\u75ab\u7597\u6cd5\u6709\u6548\u7684\u53ef\u80fd\u6027\u8d8a\u5927\uff0c\u56e0\u6b64\u7814\u7a76\u4eba\u5458\u8bd5\u56fe\u901a\u8fc7\u6210\u50cf\u6765\u8868\u5f81\u8fd9\u79cd\u73af\u5883\u5e76\u5c06\u5176\u4e0e\u60a3\u8005\u7684\u4e34\u5e8a\u53cd\u5e94\u76f8\u5173\u8054\u3002<\/p>\n \u30108\u3011Nat Commun\uff1a\u4eba\u5de5\u667a\u80fd\u52a9\u653b\u524d\u5217\u817a\u764c\u8bca\u65ad\u548c\u6cbb\u7597<\/strong><\/p>\n doi\uff1a10.1038\/s41467-018-04724-5<\/p>\n \u6765\u81ea\u745e\u5178\u7684\u79d1\u5b66\u5bb6\u4eec\u7684\u6700\u65b0\u7814\u7a76\u6210\u679c\u8868\u660e\u6570\u636e\u9a71\u4f7f\u7684AI\u53ef\u4ee5\u5e2e\u52a9\u6211\u4eec\u66f4\u6df1\u5165\u4e86\u89e3\u524d\u5217\u817a\u764c\u5982\u4f55\u53d1\u5c55\uff0c\u6700\u7ec8\u53ef\u4ee5\u5e2e\u52a9\u63d0\u9ad8\u8fd9\u79cd\u75be\u75c5\u7684\u4e34\u5e8a\u8bca\u65ad\u548c\u6cbb\u7597\u7ed3\u679c\u3002\u6bcf\u79cd\u764c\u75c7\u90fd\u662f\u72ec\u7279\u7684\uff0c\u5b83\u7684\u7279\u70b9\u968f\u7740\u65f6\u95f4\u53d8\u5316\u800c\u53d8\u5316\uff0c\u8fd9\u79cd\u6240\u8c13\u7684\u80bf\u7624\u5f02\u8d28\u6027\u662f\u7531\u4e8e\u80bf\u7624\u5185\u7ec6\u80de\u7684\u7ade\u4e89\u6027\u514b\u9686\u4ee5\u53ca\u53ef\u80fd\u589e\u52a0\u8f6c\u79fb\u6982\u7387\u7684\u83b7\u5f97\u6027\u57fa\u56e0\u7a81\u53d8\u3002<\/p>\n \u6765\u81ea\u745e\u5178\u751f\u547d\u79d1\u5b66\u5b9e\u9a8c\u5ba4\u7684\u7814\u7a76\u4eba\u5458\u5f00\u53d1\u4e86\u4e00\u79cd\u6570\u636e\u8bad\u7ec3\u7684AI\u65b9\u6cd5\u53ef\u4ee5\u5e2e\u52a9\u6211\u4eec\u66f4\u597d\u5730\u4e86\u89e3\u524d\u5217\u817a\u764c\u53ca\u5176\u5468\u56f4\u5fae\u73af\u5883\u5f02\u8d28\u6027\u76f8\u5173\u7684\u4e3b\u8981\u4e8b\u4ef6\u3002\u8fd9\u4e2a\u6765\u81ea\u745e\u5178\u7687\u5bb6\u7406\u5de5\u5b66\u9662\uff08KTH\uff09\u548c\u5361\u7f57\u6797\u65af\u5361\u7814\u7a76\u6240\u7684\u7814\u7a76\u56e2\u961f\u5728KTH\u5206\u5b50\u751f\u7269\u5b66\u6559\u6388Joakim Lundeberg\u7684\u9886\u5bfc\u4e0b\u83b7\u5f97\u4e86\u6765\u81ea6750\u4e2a\u80bf\u7624\u7ec4\u7ec7\u6837\u54c1\u7684\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b66\uff08\u4e00\u79cd\u5b9a\u91cf\u5206\u6790\u57fa\u56e0\u7684\u7ec4\u7ec7\u5b66\u65b9\u6cd5\uff0c\u7531KTH\u548c\u5361\u7f57\u6797\u65af\u5361\u7814\u7a76\u6240\u7684\u7814\u7a76\u4eba\u5458\u5171\u540c\u5f00\u53d1\uff09\u5206\u6790\u6570\u636e\u3002<\/p>\n \u30109\u3011Cell\uff1a\u5229\u7528\u4eba\u5de5\u667a\u80fd\u7ed8\u5236\u8870\u8001\u5927\u8111\u7684\u57fa\u56e0\u8868\u8fbe\u56fe\u8c31<\/strong><\/p>\n doi\uff1a10.1016\/j.cell.2018.05.057<\/p>\n \u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u6bd4\u5229\u65f6\u9c81\u6c76\u5927\u5b66\uff08VIB-KU Leuven\uff09Stein Aerts\u6559\u6388\u53ca\u5176\u56e2\u961f\u9996\u6b21\u5728\u679c\u8747\u8870\u8001\u8fc7\u7a0b\u4e2d\u7ed8\u5236\u51fa\u6bcf\u4e2a\u8111\u7ec6\u80de\u7684\u57fa\u56e0\u8868\u8fbe\u56fe\u8c31\u3002\u7531\u6b64\u4ea7\u751f\u7684\u201c\u7ec6\u80de\u56fe\u8c31\u201d\u4e3a\u5927\u8111\u5728\u8870\u8001\u8fc7\u7a0b\u4e2d\u7684\u8fd0\u4f5c\u63d0\u4f9b\u4e86\u524d\u6240\u672a\u6709\u7684\u89c1\u89e3\u3002\u8fd9\u79cd\u7ec6\u80de\u56fe\u8c31\u88ab\u8ba4\u4e3a\u662f\u5f00\u53d1\u6709\u52a9\u4e8e\u66f4\u597d\u5730\u7406\u89e3\u4eba\u7c7b\u75be\u75c5\u53d1\u5c55\u7684\u6280\u672f\u800c\u8fc8\u51fa\u91cd\u8981\u7684\u7b2c\u4e00\u6b65\u3002\u76f8\u5173\u7814\u7a76\u7ed3\u679c\u4e8e2018\u5e746\u670814\u65e5\u5728\u7ebf\u53d1\u8868\u5728Cell\u671f\u520a\u4e0a\u3002<\/p>\n \u679c\u8747\u7684\u5927\u8111\u7531\u5927\u7ea610\u4e07\u4e2a\u7ec6\u80de\u7ec4\u6210\uff0c\u5c3d\u7ba1\u5b83\u6bd4\u4eba\u8111\u5c0f\u5f97\u591a\uff0c\u4f46\u5b83\u5305\u542b\u6570\u767e\u79cd\u4e0d\u540c\u7c7b\u578b\u7684\u795e\u7ecf\u5143\u548c\u5176\u4ed6\u5f62\u6210\u590d\u6742\u7f51\u7edc\u7684\u7ec6\u80de\uff0c\u975e\u5e38\u50cf\u4eba\u7c7b\u5927\u8111\u3002\u7814\u7a76\u8005\u89e3\u91ca\u9053\uff0c\u201c\u4e3a\u4e86\u771f\u6b63\u7406\u89e3\u5927\u8111\u7684\u8fd0\u4f5c\uff0c\u5373\u4f7f\u5bf9\u50cf\u679c\u8747\u4e00\u6837\u5c0f\u7684\u6709\u673a\u4f53\uff0c\u6211\u4eec\u4e5f\u9700\u8981\u653e\u5927\u89c2\u5bdf\u6bcf\u4e2a\u7ec6\u80de\u3002\u6240\u6709\u7684\u5668\u5b98\u548c\u7ec4\u7ec7\u90fd\u7531\u8bb8\u591a\u4e0d\u540c\u7684\u7ec6\u80de\u7ec4\u6210\uff0c\u8fd9\u4e9b\u7ec6\u80de\u5f7c\u6b64\u4e4b\u95f4\u8fdb\u884c\u6c9f\u901a\u6765\u6267\u884c\u5b83\u4eec\u7684\u7279\u5b9a\u529f\u80fd\u3002\u5c3d\u7ba1\u5b83\u4eec\u5177\u6709\u76f8\u540c\u7684DNA\uff0c\u4f46\u5b83\u4eec\u90fd\u8868\u8fbe\u4e00\u7ec4\u4e0d\u540c\u7684\u57fa\u56e0\uff0c\u56e0\u6b64\u4e3a\u4e86\u7406\u89e3\u771f\u6b63\u53d1\u751f\u4e86\u4ec0\u4e48\uff0c\u6211\u4eec\u9700\u8981\u77e5\u9053\u54ea\u4e9b\u7ec6\u80de\u5728\u505a\u4ec0\u4e48\u548c\u4ec0\u4e48\u65f6\u5019\u505a\u3002\u201d<\/p>\n \u301010\u3011Science\uff1a\u5f00\u53d1\u51fa\u4eba\u5de5\u667a\u80fd\u9a71\u52a8\u7684\u9b3c\u5f71\u7ec6\u80de\u6d4b\u5b9a\u4eea\uff0c\u4e0d\u7528\u4ea7\u751f\u56fe\u50cf\u5c31\u53ef\u9ad8\u901a\u91cf\u8bc6\u522b\u548c\u5206\u9009\u7ec6\u80de<\/strong><\/p>\n doi\uff1a10.1126\/science.aan0096<\/p>\n \u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u65e5\u672c\u7814\u7a76\u4eba\u5458\u53d1\u660e\u4e86\u4e00\u79cd\u65b0\u7684\u7ec6\u80de\u8bc6\u522b\u548c\u5206\u9009\u7cfb\u7edf\uff0c\u5e76\u79f0\u4e4b\u4e3a\u9b3c\u5f71\u7ec6\u80de\u6d4b\u5b9a\u4eea\uff08Ghost Cytometry\uff09\u3002\u8fd9\u79cd\u7cfb\u7edf\u5c06\u4e00\u79cd\u65b0\u7684\u6210\u50cf\u6280\u672f\u4e0e\u4eba\u5de5\u667a\u80fd\uff08AI\uff09\u7ed3\u5408\u5728\u4e00\u8d77\u4ee5\u53f2\u65e0\u524d\u4f8b\u5730\u9ad8\u901a\u91cf\u901f\u5ea6\u8bc6\u522b\u548c\u5206\u9009\u7ec6\u80de\u3002\u4ed6\u4eec\u5e0c\u671b\u4ed6\u4eec\u7684\u65b9\u6cd5\u5c06\u7528\u4e8e\u8bc6\u522b\u548c\u5206\u9009\u5728\u60a3\u8005\u8840\u6db2\u4e2d\u7684\u5faa\u73af\u764c\u7ec6\u80de\u3001\u80fd\u591f\u52a0\u901f\u836f\u7269\u53d1\u73b0\u548c\u6539\u8fdb\u57fa\u4e8e\u7ec6\u80de\u7684\u533b\u5b66\u7597\u6cd5\u7684\u7597\u6548\u3002<\/p>\n 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