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mRNA\u75ab\u82d7\u65e0\u6cd5\u8fdb\u5165\u7ec6\u80de\u6838<\/strong><\/p>\n

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\u771f\u76f8\uff1a\u5bf9\u6b64\uff0c\u7f8e\u56fd\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u533b\u5b66\u9662\u75c5\u7406\u53ca\u5b9e\u9a8c\u533b\u836f\u7cfb\u526f\u6559\u6388\u5f20\u6d2a\u6d9b\u8868\u793a\uff0cmRNA\u75ab\u82d7\u7684\u7eb3\u7c73\u5fae\u7c92\u8f7d\u4f53\uff0c\u53ea\u662f\u5c06\u75c5\u6bd2\u7684\u57fa\u56e0\u7247\u6bb5\u9001\u5165\u7ec6\u80de\u8d28\uff0c\u6839\u672c\u4e0d\u4f1a\u8fdb\u5165\u7ec6\u80de\u6838\u3002\u5b83\u8fde\u7ec6\u80de\u6838\u90fd\u8fdb\u4e0d\u53bb\uff0c\u5c31\u66f4\u4e0d\u8981\u8bf4\u88ab\u6574\u5408\u5230\u4eba\u7684\u57fa\u56e0\u7ec4\u91cc\u4e86\u3002<\/p>\n

mRNA\u75ab\u82d7\u6280\u672f\u59cb\u4e8e1989\u5e74\uff0c\u6b64\u524d\u8be5\u6280\u672f\u4e3b\u8981\u88ab\u7528\u4e8e\u6cbb\u7597\u764c\u75c7\uff0c\u8fd9\u662f\u5176\u9996\u6b21\u5728\u4f20\u67d3\u75c5\u9884\u9632\u9886\u57df\u88ab\u5927\u89c4\u6a21\u4f7f\u7528\u3002\u5728\u7814mRNA\u65b0\u51a0\u75ab\u82d7\u57fa\u672c\u91c7\u7528\u65b0\u51a0\u75c5\u6bd2\u523a\u7a81S\u86cb\u767d\u4f5c\u4e3a\u6297\u539f\uff0c\u901a\u8fc7\u7eb3\u7c73\u8f7d\u4f53\u6280\u672f\u5c06mRNA\u75ab\u82d7\u5305\u88f9\u5728\u7eb3\u7c73\u9897\u7c92\u4e2d\u3002<\/p>\n

\u79d1\u5b66\u7814\u7a76\u53d1\u73b0\uff0c\u5728\u4eca\u5929\u7684\u4eba\u4f53\u57fa\u56e0\u7ec4\u4e2d\uff0c\u7ea68%\u7684\u57fa\u56e0\u6765\u81ea\u75c5\u6bd2\uff0c\u800c\u5177\u6709\u8fd9\u7c7b\u80fd\u529b\u7684\u75c5\u6bd2\uff0c\u5c31\u662f\u53e4\u8001\u7684\u9006\u8f6c\u5f55\u75c5\u6bd2\u3002<\/p>\n

\u201c\u65b0\u51a0\u75c5\u6bd2\u662fRNA\uff08\u6838\u7cd6\u6838\u9178\uff09\u75c5\u6bd2\uff0c\u4f46\u4e0d\u662f\u9006\u8f6c\u5f55RNA\u75c5\u6bd2\uff0c\u6240\u4ee5\u65b0\u51a0\u75c5\u6bd2\u7684\u57fa\u56e0\u4e0d\u4f1a\u88ab\u6574\u5408\u5230\u4eba\u4f53\u67d3\u8272\u4f53\u4e2d\uff0c\u8fd9\u662f\u5e38\u8bc6\u3002\u201d\u5f20\u6d2a\u6d9b\u6307\u51fa\u3002<\/p>\n

\u75ab\u82d7\u63a5\u79cd\u53cd\u5e94\u8d8a\u5f3a\uff0c\u6548\u679c\u8d8a\u597d\uff1f<\/strong><\/p>\n

\u4e0d\u826f\u53cd\u5e94\u4e0e\u514d\u75ab\u6548\u679c\u65e0\u76f4\u63a5\u5173\u8054<\/strong><\/p>\n

\u5f00\u5c55\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u662f\u63a7\u5236\u75ab\u60c5\u4f20\u64ad\u7684\u6709\u6548\u624b\u6bb5\u3002\u53ef\u75ab\u82d7\u6253\u8fdb\u53bb\u6548\u679c\u5982\u4f55\uff0c\u770b\u4e0d\u89c1\u3001\u6478\u4e0d\u7740\uff0c\u4e8e\u662f\u201c\u6709\u5fc3\u4eba\u201d\u4fbf\u5728\u7f51\u4e0a\u6563\u5e03\u201c\u75ab\u82d7\u63a5\u79cd\u53cd\u5e94\u8d8a\u5f3a\u70c8\uff0c\u514d\u75ab\u6548\u679c\u5c31\u8d8a\u597d\u201d\u7684\u4f20\u8a00\u3002<\/p>\n

\u771f\u76f8\uff1a\u591a\u4f4d\u4e13\u5bb6\u8868\u793a\uff0c\u8fd9\u79cd\u8bf4\u6cd5\u7ad9\u4e0d\u4f4f\u811a\u3002\u63a5\u79cd\u65b0\u51a0\u75ab\u82d7\u540e\u7684\u4e0d\u826f\u53cd\u5e94\u56e0\u4eba\u800c\u5f02\uff0c\u5b58\u5728\u4e2a\u4f53\u5dee\u5f02\u3002\u63a5\u79cd\u75ab\u82d7\u540e\u53cd\u5e94\u5f3a\uff0c\u5e76\u4e0d\u610f\u5473\u7740\u514d\u75ab\u6548\u679c\u597d\uff0c\u4e24\u8005\u6ca1\u6709\u76f4\u63a5\u5173\u7cfb\u3002<\/p>\n

\u63a5\u79cd\u65b0\u51a0\u75ab\u82d7\u540e\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f\u60c5\u51b5\u4e0e\u5df2\u5e7f\u6cdb\u5e94\u7528\u7684\u5176\u4ed6\u75ab\u82d7\u57fa\u672c\u7c7b\u4f3c\uff0c\u7edd\u5927\u591a\u6570\u4e3a\u4e00\u822c\u53cd\u5e94\uff0c\u4e3b\u8981\u8868\u73b0\u4e3a\u63a5\u79cd\u90e8\u4f4d\u7ea2\u80bf\u3001\u786c\u7ed3\u3001\u75bc\u75db\u7b49\u5c40\u90e8\u53cd\u5e94\uff0c\u4ee5\u53ca\u53d1\u70ed\u3001\u4e4f\u529b\u7b49\u5168\u8eab\u53cd\u5e94\u3002<\/p>\n

\u6839\u636e\u4e2d\u56fd\u75be\u75c5\u9884\u9632\u63a7\u5236\u4e2d\u5fc3\u4e8e5\u670828\u65e5\u53d1\u5e03\u7684\u6211\u56fd\u65b0\u51a0\u80ba\u708e\u75ab\u82d7\u63a5\u79cd\u4e0d\u826f\u53cd\u5e94\u76d1\u6d4b\u60c5\u51b5\uff0c\u6211\u56fd\u8be5\u75ab\u82d7\u7684\u4e00\u822c\u53cd\u5e94\u3001\u5f02\u5e38\u53cd\u5e94\u53d1\u751f\u7387\u5747\u4f4e\u4e8e2019\u5e74\u6211\u56fd\u5176\u4ed6\u5404\u7c7b\u75ab\u82d7\u7684\u5e73\u5747\u62a5\u544a\u6c34\u5e73\u3002<\/p>\n

\u4e2d\u56fd\u75be\u75c5\u9884\u9632\u63a7\u5236\u4e2d\u5fc3\u9996\u5e2d\u4e13\u5bb6\u3001\u7814\u7a76\u5458\u90b5\u4e00\u9e23\u4e5f\u5bf9\u6b64\u8fdb\u884c\u4e86\u8f9f\u8c23\u3002\u4ed6\u8868\u793a\uff0c\u63a5\u79cd\u75ab\u82d7\u7684\u526f\u53cd\u5e94\u4e0e\u75ab\u82d7\u4ea7\u751f\u7684\u514d\u75ab\u53cd\u5e94\u6ca1\u6709\u76f4\u63a5\u5173\u7cfb\u3002\u526f\u53cd\u5e94\u5f3a\u5e76\u4e0d\u80fd\u8bf4\u660e\u6fc0\u53d1\u51fa\u7684\u514d\u75ab\u529b\u5f3a\uff0c\u6709\u6ca1\u6709\u526f\u53cd\u5e94\u8ddf\u4f53\u8d28\u6709\u5173\uff0c\u6bd4\u5982\u8fc7\u654f\u4f53\u8d28\u7684\u4eba\u526f\u53cd\u5e94\u4f1a\u6bd4\u8f83\u5f3a\u3002\u603b\u4f53\u8bf4\u6765\uff0c\u65b0\u51a0\u80ba\u708e\u75ab\u82d7\u526f\u53cd\u5e94\u7684\u53d1\u751f\u7387\u662f\u6bd4\u8f83\u4f4e\u7684\uff0c\u4f46\u8be5\u75ab\u82d7\u7684\u4fdd\u62a4\u7387\u90fd\u572880%\u4ee5\u4e0a\uff0c\u8fd9\u4e5f\u80fd\u8bf4\u660e\u8fd9\u4e24\u8005\u4e4b\u95f4\u6ca1\u6709\u5fc5\u7136\u5173\u7cfb\u3002<\/p>\n

\u65b0\u51a0\u75ab\u82d7\u6709\u6548\u671f\u4ec5\u534a\u5e74\uff1f<\/strong><\/p>\n

\u81f3\u5c11\u534a\u5e74\uff0c\u5177\u4f53\u4fdd\u62a4\u65f6\u6548\u8fd8\u5728\u89c2\u5bdf\u4e2d<\/strong><\/p>\n

\u4eca\u5e74\uff0c\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u5728\u5168\u56fd\u6df1\u5165\u63a8\u8fdb\u7684\u540c\u65f6\uff0c\u6709\u4f20\u8a00\u79f0\uff0c\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u4fdd\u62a4\u671f\u53ea\u6709\u534a\u5e74\u3002<\/p>\n

\u771f\u76f8\uff1a\u5317\u4eac\u5e02\u75be\u75c5\u9884\u9632\u63a7\u5236\u4e2d\u5fc3\u526f\u4e3b\u4efb\u5e9e\u661f\u706b\u8868\u793a\uff0c\u65b0\u51a0\u75ab\u82d7\u7684\u4fdd\u62a4\u671f\u5e76\u975e\u4ec5\u6709\u534a\u5e74\u3002\u5404\u6709\u5173\u90e8\u95e8\u8fd8\u5728\u6301\u7eed\u6536\u96c6\u63a5\u79cd\u4eba\u7fa4\u6297\u4f53\u6c34\u5e73\u7684\u6570\u636e\uff0c\u5bc6\u5207\u76d1\u6d4b\u5176\u63a5\u79cd\u540e\u7684\u4fdd\u62a4\u6548\u529b\u3002<\/p>\n

\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d1\u5e03\u7684\u300a\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u9884\u9632\u7528\u75ab\u82d7\u4e34\u5e8a\u8bc4\u4ef7\u6307\u5bfc\u539f\u5219\uff08\u8bd5\u884c\uff09\u300b\u8981\u6c42\uff0c\u5728\u6211\u56fd\u4e0a\u5e02\u7684\u65b0\u51a0\u75ab\u82d7\u81f3\u5c11\u8981\u63d0\u4f9b6\u4e2a\u6708\u7684\u4fdd\u62a4\u65f6\u95f4\u3002<\/p>\n

\u5168\u56fd\u4eba\u5927\u4ee3\u8868\u3001\u56fd\u836f\u96c6\u56e2\u56fd\u836f\u63a7\u80a1\u8463\u4e8b\u957f\u4e8e\u6e05\u660e\u5728\u4eca\u5e74\u4e24\u4f1a\u4e0a\u900f\u9732\uff0c2020\u5e743\u6708\uff0c\u8be5\u96c6\u56e2\u56db\u7ea7\u4f01\u4e1a\u515a\u653f\u8d1f\u8d23\u4eba\u201c\u4ee5\u8eab\u8bd5\u836f\u201d\uff0c\u7ecf\u8fc71\u5e74\u7684\u6297\u4f53\u6301\u7eed\u8ddf\u8e2a\u76d1\u6d4b\uff0c\u76ee\u524d\u5176\u4f53\u5185\u6297\u4f53\u6c34\u5e73\u4ecd\u5904\u5728\u8f83\u9ad8\u72b6\u6001\uff0c\u672a\u51fa\u73b0\u660e\u663e\u4e0b\u964d\u3002<\/p>\n

\u5f53\u7136\uff0c\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u540e\u4ea7\u751f\u7684\u6297\u4f53\u6c34\u5e73\u5b58\u5728\u4e2a\u4f53\u5dee\u5f02\u3002\u4e0a\u8ff0\u201c\u4ee5\u8eab\u8bd5\u836f\u201d\u7684\u4e2a\u4f8b\u6216\u8bb8\u4e0d\u8db3\u4ee5\u8bf4\u660e\u4ec0\u4e48\uff0c\u4f46\u5374\u91ca\u653e\u4e86\u4e00\u4e2a\u4fe1\u53f7\uff1a\u65b0\u51a0\u75ab\u82d7\u7684\u4fdd\u62a4\u65f6\u957f\u6216\u88ab\u90e8\u5206\u6c11\u4f17\u4f4e\u4f30\u4e86\u3002<\/p>\n

\u201c\u534a\u5e74\u201d\u4ec5\u662f\u4ea7\u54c1\u5408\u683c\u548c\u4e0a\u5e02\u7684\u5e95\u7ebf\uff0c\u4fdd\u62a4\u671f\u7a76\u7adf\u662f\u591a\u4e45\uff0c\u65f6\u95f4\u7ec8\u4f1a\u7ed9\u51fa\u7b54\u6848\u3002<\/p>\n

\u65b0\u51a0\u75c5\u6bd2\u4f1a\u53d8\u5f02\uff0c\u75ab\u82d7\u6253\u4e86\u4e5f\u65e0\u7528\uff1f<\/strong><\/p>\n

\u63a5\u79cd\u75ab\u82d7\u53ef\u5efa\u7acb\u57fa\u7840\u514d\u75ab\u5c4f\u969c<\/strong><\/p>\n

\u4eca\u5e74\u5e74\u521d\uff0c\u5168\u56fd\u5927\u89c4\u6a21\u5f00\u5c55\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u4f0a\u59cb\uff0c\u4e0d\u5c11\u4eba\u5bf9\u6253\u75ab\u82d7\u5b58\u5728\u5404\u79cd\u5404\u6837\u7684\u987e\u8651\u3002\u5176\u4e2d\u201c\u73b0\u5728\u7684\u75ab\u82d7\u53ea\u662f\u9488\u5bf9\u5f53\u4e0b\u6d41\u884c\u7684\u65b0\u51a0\u75c5\u6bd2\uff0c\u75c5\u6bd2\u53d8\u5f02\u540e\u75ab\u82d7\u5c31\u6ca1\u7528\u4e86\u201d\u7684\u8bf4\u6cd5\u88ab\u5f88\u591a\u4eba\u8ba4\u540c\u3002<\/p>\n

\u771f\u76f8\uff1a\u90b5\u4e00\u9e23\u8868\u793a\uff0c\u65b0\u51a0\u75ab\u82d7\u4e0d\u4f1a\u767d\u6253\u3002\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u540e\u4f1a\u4e3a\u63a5\u79cd\u8005\u5efa\u7acb\u62b5\u5fa1\u65b0\u51a0\u75c5\u6bd2\u7684\u57fa\u7840\u514d\u75ab\u529b\u3002<\/p>\n

\u90b5\u4e00\u9e23\u8868\u793a\uff0c\u5728\u65b0\u51a0\u75c5\u6bd2\u53d8\u5f02\u682a\u9762\u524d\uff0c\u65b0\u51a0\u75ab\u82d7\u8bf1\u5bfc\u7684\u4e2d\u548c\u6297\u4f53\u6c34\u5e73\u53ef\u80fd\u4f1a\u6709\u6240\u4e0b\u964d\uff0c\u5373\u75ab\u82d7\u7684\u4fdd\u62a4\u6548\u529b\u53ef\u80fd\u4f1a\u4e0b\u964d\u3002\u4e0d\u8fc7\u53ea\u8981\u63a5\u79cd\u4e86\uff0c\u75ab\u82d7\u5c31\u4f1a\u4e3a\u63a5\u79cd\u8005\u6784\u5efa\u9488\u5bf9\u65b0\u51a0\u75c5\u6bd2\u7684\u57fa\u7840\u514d\u75ab\u529b\u3002\u5373\u4fbf\u75c5\u6bd2\u53d8\u5f02\u682a\u9003\u8131\u75ab\u82d7\u9632\u62a4\u5c4f\u969c\u7684\u80fd\u529b\u53d8\u5f3a\u4e86\uff0c\u4ecd\u53ef\u8865\u6253\u65b0\u7684\u53d8\u5f02\u682a\u75ab\u82d7\u4f5c\u4e3a\u52a0\u5f3a\u9488\u3002\u5982\u6b64\u4e00\u6765\uff0c\u52a0\u5f3a\u9488\u5c31\u53ef\u5728\u5df2\u6709\u514d\u75ab\u57fa\u7840\u4e0a\uff0c\u5feb\u901f\u6fc0\u53d1\u51fa\u4eba\u4f53\u5e94\u5bf9\u53d8\u5f02\u682a\u75c5\u6bd2\u7684\u514d\u75ab\u4fdd\u62a4\u529b\u3002<\/p>\n

\u6b64\u5916\uff0c\u6839\u636e\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u6700\u65b0\u53d1\u5e03\u7684\u4fe1\u606f\uff0c\u4ece\u5168\u7403\u5bf9\u65b0\u51a0\u75c5\u6bd2\u53d8\u5f02\u7684\u76d1\u6d4b\u60c5\u51b5\u770b\uff0c\u5c1a\u65e0\u8bc1\u636e\u8bc1\u660e\u5728\u75c5\u6bd2\u53d8\u5f02\u682a\u9762\u524d\uff0c\u73b0\u6709\u65b0\u51a0\u75ab\u82d7\u4f1a\u5931\u6548\u3002<\/p>\n

\u75c5\u6bd2\u7bc7<\/strong><\/p>\n

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